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IFN-lambda preferably inhibits PEDV infection of porcine intestinal epithelial cells compared with IFN-alpha

In contrast to type I interferons that target various types of cells and organs, interferon lambda (IFN-L) primarily acts on mucosal epithelial cells and exhibits robust antiviral activity within the mucosal surface. Porcine epidemic diarrhea virus (PEDV), which causes high morbidity and mortality i...

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Detalles Bibliográficos
Autores principales: Li, Lin, Fu, Fang, Xue, Mei, Chen, Weiye, Liu, Jin, Shi, Hongyan, Chen, Jianfei, Bu, Zhigao, Feng, Li, Liu, Pinghuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113730/
https://www.ncbi.nlm.nih.gov/pubmed/28109912
http://dx.doi.org/10.1016/j.antiviral.2017.01.012