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Prophylactic efficacy of a human monoclonal antibody against MERS-CoV in the common marmoset

Effective antiviral treatments for MERS-CoV are urgently needed. LCA60 is a MERS-CoV-neutralizing monoclonal antibody isolated from a convalescent MERS patient. Previously, it was shown that treatment with LCA60 resulted in reduced disease and virus titers in mouse models of MERS-CoV infection. Here...

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Detalles Bibliográficos
Autores principales: de Wit, Emmie, Feldmann, Friederike, Horne, Eva, Okumura, Atsushi, Cameroni, Elisabetta, Haddock, Elaine, Saturday, Greg, Scott, Dana, Gopal, Robin, Zambon, Maria, Corti, Davide, Feldmann, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113761/
https://www.ncbi.nlm.nih.gov/pubmed/30684561
http://dx.doi.org/10.1016/j.antiviral.2019.01.016