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Celastrol inhibits dengue virus replication via up-regulating type I interferon and downstream interferon-stimulated responses

ETHNOPHARMACOLOGICAL RELEVANCE AND AIM OF THE STUDY: Tripterygium wilfordii (lei gong teng; Thunder of God Vine), a member of the Celastraceae family, is a medicinal plant used to treat a range of illnesses. Celastrol is a quinone methide triterpene and the most abundant bioactive constituent isolat...

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Detalles Bibliográficos
Autores principales: Yu, Jung-Sheng, Tseng, Chin-Kai, Lin, Chun-Kuang, Hsu, Yao-Chin, Wu, Yu-Hsuan, Hsieh, Ching-Liang, Lee, Jin-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113783/
https://www.ncbi.nlm.nih.gov/pubmed/27847245
http://dx.doi.org/10.1016/j.antiviral.2016.11.010