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Disulfiram can inhibit MERS and SARS coronavirus papain-like proteases via different modes

Severe acute respiratory syndrome coronavirus (SARS-CoV) emerged in southern China in late 2002 and caused a global outbreak with a fatality rate around 10% in 2003. Ten years later, a second highly pathogenic human CoV, MERS-CoV, emerged in the Middle East and has spread to other countries in Europ...

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Detalles Bibliográficos
Autores principales: Lin, Min-Han, Moses, David C., Hsieh, Chih-Hua, Cheng, Shu-Chun, Chen, Yau-Hung, Sun, Chiao-Yin, Chou, Chi-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113793/
https://www.ncbi.nlm.nih.gov/pubmed/29289665
http://dx.doi.org/10.1016/j.antiviral.2017.12.015