Cellular protein GLTSCR2: A valuable target for the development of broad-spectrum antivirals

Viral infection induces translocation of the nucleolar protein GLTSCR2 from the nucleus to the cytoplasm, resulting in attenuation of the type I interferon IFN-β. Addressing the role of GLTSCR2 in viral replication, we detect that knocking down GLTSCR2 by shRNAs results in significant suppression of...

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Detalles Bibliográficos
Autores principales: Li, Cui-Cui, Dong, Hui-Jun, Wang, Peng, Meng, Wen, Chi, Xiao-Jing, Han, Shi-Chong, Ning, Shuo, Wang, Chuang, Wang, Xiao-Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113796/
https://www.ncbi.nlm.nih.gov/pubmed/28286234
http://dx.doi.org/10.1016/j.antiviral.2017.03.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113796/
https://www.ncbi.nlm.nih.gov/pubmed/28286234
http://dx.doi.org/10.1016/j.antiviral.2017.03.004

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