Cargando…

Cellular protein GLTSCR2: A valuable target for the development of broad-spectrum antivirals

Viral infection induces translocation of the nucleolar protein GLTSCR2 from the nucleus to the cytoplasm, resulting in attenuation of the type I interferon IFN-β. Addressing the role of GLTSCR2 in viral replication, we detect that knocking down GLTSCR2 by shRNAs results in significant suppression of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Cui-Cui, Dong, Hui-Jun, Wang, Peng, Meng, Wen, Chi, Xiao-Jing, Han, Shi-Chong, Ning, Shuo, Wang, Chuang, Wang, Xiao-Jia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113796/ https://www.ncbi.nlm.nih.gov/pubmed/28286234 http://dx.doi.org/10.1016/j.antiviral.2017.03.004

Ejemplares similares

The nucleolar protein GLTSCR2 is required for efficient viral replication
por: Wang, Peng, et al.
Publicado: (2016)

Broad-spectrum antiviral agents
por: Zhu, Jun-Da, et al.
Publicado: (2015)

Broad-Spectrum Antivirals Derived from Natural Products
por: Tian, Wen-Jun, et al.
Publicado: (2023)

The Natural Compound Homoharringtonine Presents Broad Antiviral Activity In Vitro and In Vivo
por: Dong, Hui-Jun, et al.
Publicado: (2018)

GLTSCR2 is an upstream negative regulator of nucleophosmin in cervical cancer
por: Kim, Jee-Youn, et al.
Publicado: (2015)

GLTSCR2 promotes the nucleoplasmic translocation and subsequent degradation of nucleolar ARF
por: Lee, Sun, et al.
Publicado: (2016)

Loss of GLTSCR1 causes congenital heart defects by regulating NPPA transcription
por: Han, Fengyan, et al.
Publicado: (2023)

Broad-Spectrum Antiviral Therapeutics
por: Rider, Todd H., et al.
Publicado: (2011)

Broad-Spectrum Antivirals and Antiviral Drug Combinations
por: Oksenych, Valentyn, et al.
Publicado: (2022)

GLTSCR1 Negatively Regulates BRD4‐Dependent Transcription Elongation and Inhibits CRC Metastasis
por: Han, Fengyan, et al.
Publicado: (2019)

Broad-Spectrum Antivirals and Antiviral Combinations: An Editorial Update
por: Kainov, Denis, et al.
Publicado: (2022)

Modified cyclodextrins as broad-spectrum antivirals
por: Jones, Samuel T., et al.
Publicado: (2020)

Broad-Spectrum Antiviral Natural Products from the Marine-Derived Penicillium sp. IMB17-046
por: Li, Jiao, et al.
Publicado: (2019)

Epimedium koreanum Nakai Displays Broad Spectrum of Antiviral Activity in Vitro and in Vivo by Inducing Cellular Antiviral State
por: Cho, Won-Kyung, et al.
Publicado: (2015)

Nucleolar Localization of GLTSCR2/PICT-1 Is Mediated by Multiple Unique Nucleolar Localization Sequences
por: Kalt, Inna, et al.
Publicado: (2012)

Identification of tanshinone I as cap-dependent endonuclease inhibitor with broad-spectrum antiviral effect
por: He, Xiaoxue, et al.
Publicado: (2023)

Broad-spectrum antivirals against viral fusion
por: Vigant, Frederic, et al.
Publicado: (2015)

Arbidol as a broad-spectrum antiviral: An update
por: Blaising, Julie, et al.
Publicado: (2014)

Broad-Spectrum Antiviral Strategies and Nucleoside Analogues
por: Geraghty, Robert J., et al.
Publicado: (2021)

dsRNA as broad-spectrum antiviral therapeutics
por: Xu, Congfei
Publicado: (2022)

GLTSCR1 coordinates alternative splicing and transcription elongation of ZO1 to regulate colorectal cancer progression
por: Han, Fengyan, et al.
Publicado: (2022)

Enhancing the Antiviral Potency of Nucleobases for Potential Broad-Spectrum Antiviral Therapies
por: Soto-Acosta, Ruben, et al.
Publicado: (2021)

Reversible rearrangement of the cellular cytoskeleton: A key to the broad-spectrum antiviral activity of novel amphiphilic polymers()
por: Dabrowska, Agnieszka, et al.
Publicado: (2023)

The broad-spectrum antiviral functions of IFIT and IFITM proteins
por: Diamond, Michael S., et al.
Publicado: (2012)

Drug repurposing for new, efficient, broad spectrum antivirals
por: García-Serradilla, Moisés, et al.
Publicado: (2019)

Tilorone, a Broad-Spectrum Antiviral for Emerging Viruses
por: Ekins, Sean, et al.
Publicado: (2020)

Conserved coronavirus proteins as targets of broad-spectrum antivirals
por: Melo-Filho, Cleber C., et al.
Publicado: (2022)

Near-Infrared Dyes: Towards Broad-Spectrum Antivirals
por: Mariewskaya, Kseniya A., et al.
Publicado: (2022)

Preparing for the next viral threat with broad-spectrum antivirals
por: Karim, Marwah, et al.
Publicado: (2023)

Clofazimine derivatives as potent broad-spectrum antiviral agents with dual-target mechanism
por: Zhang, Xintong, et al.
Publicado: (2022)

SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target
por: Yuan, Shuofeng, et al.
Publicado: (2019)

Chicken DNA Sensing cGAS-STING Signal Pathway Mediates Broad Spectrum Antiviral Functions
por: Li, Shuangjie, et al.
Publicado: (2020)

Discovery of Potent Broad Spectrum Antivirals Derived from Marine Actinobacteria
por: Raveh, Avi, et al.
Publicado: (2013)

The Broad-Spectrum Antiviral Protein ZAP Restricts Human Retrotransposition
por: Goodier, John L., et al.
Publicado: (2015)

Identification of Broad-Spectrum Antiviral Compounds by Targeting Viral Entry
por: Mazzon, Michela, et al.
Publicado: (2019)

Targeting viral entry as a strategy for broad-spectrum antivirals
por: Mazzon, Michela, et al.
Publicado: (2019)

Broad-spectrum antiviral activity of carbodine, the carbocyclic analogue of cytidine
por: De Clercq, Erik, et al.
Publicado: (1990)

Nitazoxanide: A first-in-class broad-spectrum antiviral agent
por: Rossignol, Jean-François
Publicado: (2014)

Novel activities of safe-in-human broad-spectrum antiviral agents
por: Ianevski, Aleksandr, et al.
Publicado: (2018)

Discovery and development of safe-in-man broad-spectrum antiviral agents
por: Andersen, Petter I., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8l66rm9kmamfl1tcr3g5vbcuc3