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Triggering unfolded protein response by 2-Deoxy-d-glucose inhibits porcine epidemic diarrhea virus propagation

The unfolded protein response (UPR) is cyto-protective machinery elicited towards an influx of large amount of protein synthesis in the endoplasmic reticulum (ER). Extensive studies suggest that the UPR can also be activated during virus infection. In the present studies, we first evaluated if porci...

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Detalles Bibliográficos
Autores principales: Wang, Yue, Li, Jia-rong, Sun, Ming-xia, Ni, Bo, Huan, Changchao, Huang, Li, Li, Chen, Fan, Hong-jie, Ren, Xiao-feng, Mao, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113873/
https://www.ncbi.nlm.nih.gov/pubmed/24681123
http://dx.doi.org/10.1016/j.antiviral.2014.03.007