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A microarray of ubiquitylated proteins for profiling deubiquitylase activity reveals the critical roles of both chain and substrate()
Substrate ubiquitylation is a reversible process critical to cellular homeostasis that is often dysregulated in many human pathologies including cancer and neurodegeneration. Elucidating the mechanistic details of this pathway could unlock a large store of information useful to the design of diagnos...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier B.V.
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113913/ https://www.ncbi.nlm.nih.gov/pubmed/22626734 http://dx.doi.org/10.1016/j.bbamcr.2012.05.006 |