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Emodin inhibits current through SARS-associated coronavirus 3a protein

The open-reading-frame 3a of SARS coronavirus (SARS-CoV) had been demonstrated previously to form a cation-selective channel that may become expressed in the infected cell and is then involved in virus release. Drugs that inhibit the ion channel formed by the 3a protein can be expected to inhibit vi...

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Detalles Bibliográficos
Autores principales: Schwarz, Silvia, Wang, Kai, Yu, Wenjing, Sun, Bing, Schwarz, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114100/
https://www.ncbi.nlm.nih.gov/pubmed/21356245
http://dx.doi.org/10.1016/j.antiviral.2011.02.008