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Inhibition of SARS-CoV replication cycle by small interference RNAs silencing specific SARS proteins, 7a/7b, 3a/3b and S

The severe acute respiratory syndrome coronavirus (SARS CoV) genome has 14 potential open reading frames (ORFs). The first ORF is translated from the full-length genomic mRNA while the remaining ORFs are translated from eight subgeomic RNAs (sgRNAs). In this study, we designed small interference RNA...

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Detalles Bibliográficos
Autores principales: Åkerström, Sara, Mirazimi, Ali, Tan, Yee-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114101/
https://www.ncbi.nlm.nih.gov/pubmed/17112601
http://dx.doi.org/10.1016/j.antiviral.2006.10.008