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Effect of pressure on refolding of recombinant pentameric cholera toxin B
The production of recombinant proteins is an essential tool for the expansion of modern biological research and biotechnology. The expression of heterologous proteins in Escherichia coli often results in an incomplete folding process that leads to the accumulation of inclusion bodies (IB), aggregate...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114129/ https://www.ncbi.nlm.nih.gov/pubmed/24445168 http://dx.doi.org/10.1016/j.jbiotec.2013.12.006 |