Role of the viral hemagglutinin in the anti-influenza virus activity of newly synthesized polycyclic amine compounds

We here report on the synthesis of new series of polycyclic amines initially designed as ring-rearranged analogs of amantadine and featuring pentacyclo, hexacyclo, and octacyclo rings. A secondary amine, 3-azahexacyclo[7.6.0.0(1,5).0(5,12).0(6,10).0(11,15)]pentadeca-7,13-diene, 3, effectively inhibi...

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Detalles Bibliográficos
Autores principales: Torres, Eva, Duque, María D., Vanderlinden, Evelien, Ma, Chunlong, Pinto, Lawrence H., Camps, Pelayo, Froeyen, Mathy, Vázquez, Santiago, Naesens, Lieve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114147/
https://www.ncbi.nlm.nih.gov/pubmed/23800838
http://dx.doi.org/10.1016/j.antiviral.2013.06.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114147/
https://www.ncbi.nlm.nih.gov/pubmed/23800838
http://dx.doi.org/10.1016/j.antiviral.2013.06.006

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