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Role of the viral hemagglutinin in the anti-influenza virus activity of newly synthesized polycyclic amine compounds
We here report on the synthesis of new series of polycyclic amines initially designed as ring-rearranged analogs of amantadine and featuring pentacyclo, hexacyclo, and octacyclo rings. A secondary amine, 3-azahexacyclo[7.6.0.0(1,5).0(5,12).0(6,10).0(11,15)]pentadeca-7,13-diene, 3, effectively inhibi...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier B.V.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114147/ https://www.ncbi.nlm.nih.gov/pubmed/23800838 http://dx.doi.org/10.1016/j.antiviral.2013.06.006 |