GSK983: A novel compound with broad-spectrum antiviral activity

GSK983, a novel tetrahydrocarbazole, inhibits the replication of a variety of unrelated viruses in vitro with EC(50) values of 5–20 nM. Both replication of the adenovirus Ad-5 and the polyoma virus SV-40, and episomal maintenance of human papillomaviruses (HPV) and Epstein-Barr virus (EBV) are susce...

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Detalles Bibliográficos
Autores principales: Harvey, Robert, Brown, Kevin, Zhang, Qin, Gartland, Margaret, Walton, Leslie, Talarico, Christine, Lawrence, Wendell, Selleseth, Dean, Coffield, Neil, Leary, Jeffry, Moniri, Kelly, Singer, Sara, Strum, Jay, Gudmundsson, Kristjan, Biron, Karen, Romines, Karen R., Sethna, Phiroze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114156/
https://www.ncbi.nlm.nih.gov/pubmed/19187793
http://dx.doi.org/10.1016/j.antiviral.2008.12.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114156/
https://www.ncbi.nlm.nih.gov/pubmed/19187793
http://dx.doi.org/10.1016/j.antiviral.2008.12.015

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