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Cholesterol is important for a post-adsorption step in the entry process of transmissible gastroenteritis virus

Cholesterol is a major constituent of detergent-resistant membrane microdomains (DRMs). We localized transmissible gastroenteritis virus (TGEV) spike (S) protein in DRMs in the viral envelope. Though S protein was not solubilized by cold non-ionic detergents, this behavior was unchanged when cholest...

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Detalles Bibliográficos
Autores principales: Yin, Jiechao, Glende, Joerg, Schwegmann-Wessels, Christel, Enjuanes, Luis, Herrler, Georg, Ren, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114218/
https://www.ncbi.nlm.nih.gov/pubmed/20951168
http://dx.doi.org/10.1016/j.antiviral.2010.10.002