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Induced pluripotent stem cell‐based modeling of mutant LRRK2‐associated Parkinson's disease

Recent advances in cell reprogramming have enabled assessment of disease‐related cellular traits in patient‐derived somatic cells, thus providing a versatile platform for disease modeling and drug development. Given the limited access to vital human brain cells, this technology is especially relevan...

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Detalles Bibliográficos
Autores principales: Weykopf, Beatrice, Haupt, Simone, Jungverdorben, Johannes, Flitsch, Lea Jessica, Hebisch, Matthias, Liu, Guang‐Hui, Suzuki, Keiichiro, Belmonte, Juan Carlos Izpisua, Peitz, Michael, Blaess, Sandra, Till, Andreas, Brüstle, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114274/
https://www.ncbi.nlm.nih.gov/pubmed/30656775
http://dx.doi.org/10.1111/ejn.14345