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Induced pluripotent stem cell‐based modeling of mutant LRRK2‐associated Parkinson's disease
Recent advances in cell reprogramming have enabled assessment of disease‐related cellular traits in patient‐derived somatic cells, thus providing a versatile platform for disease modeling and drug development. Given the limited access to vital human brain cells, this technology is especially relevan...
Autores principales: | Weykopf, Beatrice, Haupt, Simone, Jungverdorben, Johannes, Flitsch, Lea Jessica, Hebisch, Matthias, Liu, Guang‐Hui, Suzuki, Keiichiro, Belmonte, Juan Carlos Izpisua, Peitz, Michael, Blaess, Sandra, Till, Andreas, Brüstle, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114274/ https://www.ncbi.nlm.nih.gov/pubmed/30656775 http://dx.doi.org/10.1111/ejn.14345 |
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