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Dual roles of calpain in facilitating Coxsackievirus B3 replication and prompting inflammation in acute myocarditis

BACKGROUND: Viral myocarditis (VMC) treatment has long been lacking of effective methods. Our former studies indicated roles of calpain in VMC pathogenesis. This study aimed at verifying the potential of calpain in Coxsackievirus B3 (CVB3)-induced myocarditis treatment. METHODS: A transgenic mouse o...

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Detalles Bibliográficos
Autores principales: Li, Minghui, Su, Yangang, Yu, Yong, Yu, Ying, Wang, Xinggang, Zou, Yunzeng, Ge, Junbo, Chen, Ruizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ireland Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114300/
https://www.ncbi.nlm.nih.gov/pubmed/27472894
http://dx.doi.org/10.1016/j.ijcard.2016.07.121