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Antiviral therapies targeting host ER alpha-glucosidases: Current status and future directions

Endoplasmic reticulum (ER)-resident α-glucosidases I and II sequentially trim the three terminal glucose moieties on N-linked glycans attached to nascent glycoproteins. These reactions are the first steps of N-linked glycan processing and are essential for proper folding and function of many glycopr...

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Detalles Bibliográficos
Autores principales: Chang, Jinhong, Block, Timothy M., Guo, Ju-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114303/
https://www.ncbi.nlm.nih.gov/pubmed/23816430
http://dx.doi.org/10.1016/j.antiviral.2013.06.011