Dynamic template-assisted strategies in fragment-based drug discovery

Fragment-based methods for drug discovery are increasingly popular because they provide drug leads with greater ligand efficiency than conventional high-throughput screening. However, established methods for fragment detection do not address the central question in fragment-based ligand discovery: h...

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Detalles Bibliográficos
Autores principales: Schmidt, Marco F., Rademann, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114311/
https://www.ncbi.nlm.nih.gov/pubmed/19679363
http://dx.doi.org/10.1016/j.tibtech.2009.06.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114311/
https://www.ncbi.nlm.nih.gov/pubmed/19679363
http://dx.doi.org/10.1016/j.tibtech.2009.06.001

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