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Dynamic template-assisted strategies in fragment-based drug discovery
Fragment-based methods for drug discovery are increasingly popular because they provide drug leads with greater ligand efficiency than conventional high-throughput screening. However, established methods for fragment detection do not address the central question in fragment-based ligand discovery: h...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Ltd.
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114311/ https://www.ncbi.nlm.nih.gov/pubmed/19679363 http://dx.doi.org/10.1016/j.tibtech.2009.06.001 |