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High-throughput assay using a GFP-expressing replicon for SARS-CoV drug discovery

The causative agent of severe acute respiratory syndrome (SARS) has been identified as a novel coronavirus, SARS-CoV. The development of rapid screening assays is essential for antiviral drug discovery. By using a cell line expressing a SARS-CoV subgenomic replicon, we developed a high-throughput as...

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Detalles Bibliográficos
Autores principales: Ge, Feng, Xiong, Sheng, Lin, Fu-Sen, Zhang, Zhi-Ping, Zhang, Xian-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114325/
https://www.ncbi.nlm.nih.gov/pubmed/18584889
http://dx.doi.org/10.1016/j.antiviral.2008.05.005