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Effective inhibition of hepatitis E virus replication in A549 cells and piglets by RNA interference (RNAi) targeting RNA-dependent RNA polymerase

RNA interference (RNAi) is a natural mechanism for suppressing or silencing expression of aberrant or foreign genes. It is a powerful antiviral strategy that has been widely employed to protect hosts from viral infection. Hepatitis E (HE) is an acute fulminant hepatitis in adults that has particular...

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Detalles Bibliográficos
Autores principales: Huang, Fen, Hua, Xiuguo, Yang, Shixing, Yuan, Congli, Zhang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114333/
https://www.ncbi.nlm.nih.gov/pubmed/19576249
http://dx.doi.org/10.1016/j.antiviral.2009.06.008