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In vivo growth of porcine reproductive and respiratory syndrome virus engineered nsp2 deletion mutants
Prior studies on PRRSV strain VR-2332 non-structural protein 2 (nsp2) had shown that as much as 403 amino acids could be removed from the hypervariable region without losing virus viability in vitro. We utilized selected nsp2 deletion mutants to examine in vivo growth. Young swine (4 pigs/group; 5 c...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114397/ https://www.ncbi.nlm.nih.gov/pubmed/20673840 http://dx.doi.org/10.1016/j.virusres.2010.07.024 |