Cargando…

In vivo growth of porcine reproductive and respiratory syndrome virus engineered nsp2 deletion mutants

Prior studies on PRRSV strain VR-2332 non-structural protein 2 (nsp2) had shown that as much as 403 amino acids could be removed from the hypervariable region without losing virus viability in vitro. We utilized selected nsp2 deletion mutants to examine in vivo growth. Young swine (4 pigs/group; 5 c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Faaberg, Kay S., Kehrli, Marcus E., Lager, Kelly M., Guo, Baoqing, Han, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science 2010
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114397/ https://www.ncbi.nlm.nih.gov/pubmed/20673840 http://dx.doi.org/10.1016/j.virusres.2010.07.024

Ejemplares similares

Experimental infection of United States swine with a Chinese highly pathogenic strain of porcine reproductive and respiratory syndrome virus
por: Guo, Baoqing, et al.
Publicado: (2013)

Analysis of the swine tracheobronchial lymph node transcriptomic response to infection with a Chinese highly pathogenic strain of porcine reproductive and respiratory syndrome virus
por: Miller, Laura C, et al.
Publicado: (2012)

Porcine reproductive and respiratory syndrome (PRRS): an immune dysregulatory pandemic
por: Butler, J. E., et al.
Publicado: (2014)

In-Depth Global Analysis of Transcript Abundance Levels in Porcine Alveolar Macrophages Following Infection with Porcine Reproductive and Respiratory Syndrome Virus
por: Miller, Laura C., et al.
Publicado: (2010)

Molecular Dissection of Porcine Reproductive and Respiratory Virus Putative Nonstructural Protein 2
por: Faaberg, Kay S., et al.
Publicado: (2006)

Status report on porcine epidemic diarrhea virus in the United States
por: Kehrli, Marcus E., et al.
Publicado: (2014)

Functional Properties of the Predicted Helicase of Porcine Reproductive and Respiratory Syndrome Virus
por: Bautista, Elida M., et al.
Publicado: (2002)

Complete genome comparison of porcine reproductive and respiratory syndrome virus parental and attenuated strains
por: Yuan, Shishan, et al.
Publicado: (2001)

Research Progress on NSP11 of Porcine Reproductive and Respiratory Syndrome Virus
por: Zheng, Yajie, et al.
Publicado: (2023)

Erratum to “Complete genome comparison of porcine reproductive and respiratory syndrome virus parental and attenuated strains”
por: Yuan, Shishan, et al.
Publicado: (2001)

Recombination between North American strains of porcine reproductive and respiratory syndrome virus
por: Yuan, Shishan, et al.
Publicado: (1999)

Research Progress on the NSP9 Protein of Porcine Reproductive and Respiratory Syndrome Virus
por: Sha, Huiyang, et al.
Publicado: (2022)

Research Progress on Porcine Reproductive and Respiratory Syndrome Virus NSP7 Protein
por: Li, Huawei, et al.
Publicado: (2023)

Nsp9 and Nsp10 Contribute to the Fatal Virulence of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Emerging in China
por: Li, Yan, et al.
Publicado: (2014)

Endoribonuclease activities of porcine reproductive and respiratory syndrome virus nsp11 was essential for nsp11 to inhibit IFN-β induction
por: Shi, Xibao, et al.
Publicado: (2011)

Hyper-phosphorylation of nsp2-related proteins of porcine reproductive and respiratory syndrome virus
por: Shang, Pengcheng, et al.
Publicado: (2020)

Induction of type I interferons by a novel porcine reproductive and respiratory syndrome virus isolate
por: Nan, Yuchen, et al.
Publicado: (2012)

Correction: Nsp9 and Nsp10 Contribute to the Fatal Virulence of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Emerging in China
Publicado: (2014)

Exostosin glycosyltransferase 1 reduces porcine reproductive and respiratory syndrome virus infection through proteasomal degradation of nsp3 and nsp5
por: Zhang, Xiaoxiao, et al.
Publicado: (2021)

Development and utilization of an infectious clone for porcine deltacoronavirus strain USA/IL/2014/026
por: Deng, Xufang, et al.
Publicado: (2021)

Reactomes of Porcine Alveolar Macrophages Infected with Porcine Reproductive and Respiratory Syndrome Virus
por: Jiang, Zhihua, et al.
Publicado: (2013)

Complete Genome Sequence of a Chinese Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus That Has a Further Deletion in the Nsp2 Gene
por: Ji, Guobiao, et al.
Publicado: (2016)

Correction: Exostosin glycosyltransferase 1 reduces porcine reproductive and respiratory syndrome virus infection through proteasomal degradation of nsp3 and nsp5
por: Zhang, Xiaoxiao, et al.
Publicado: (2022)

TRIM4-mediated ubiquitination of NSP2 restricts porcine reproductive and respiratory syndrome virus proliferation
por: Zhao, Mengmeng, et al.
Publicado: (2022)

Variations in NSP1 of Porcine Reproductive and Respiratory Syndrome Virus Isolated in China from 1996 to 2022
por: Zhang, Zhiqing, et al.
Publicado: (2023)

Structural insights into type I and type II of nsp4 porcine reproductive and respiratory syndrome virus (nsp4 PRRSV) by molecular dynamics simulations
por: Aeksiri, Niran, et al.
Publicado: (2017)

Structural Analysis of Porcine Reproductive and Respiratory Syndrome Virus Non-structural Protein 7α (NSP7α) and Identification of Its Interaction with NSP9
por: Chen, Jiaping, et al.
Publicado: (2017)

A Dimerization-Dependent Mechanism Drives the Endoribonuclease Function of Porcine Reproductive and Respiratory Syndrome Virus nsp11
por: Shi, Yuejun, et al.
Publicado: (2016)

Experimental inoculation of pigs with pandemic H1N1 2009 virus and HI cross‐reactivity with contemporary swine influenza virus antisera
por: Vincent, Amy L., et al.
Publicado: (2010)

Comparative in vivo analysis of the nsp15 endoribonuclease of murine, porcine and severe acute respiratory syndrome coronaviruses
por: Cao, Jianzhong, et al.
Publicado: (2012)

The Effects of the Context-Dependent Codon Usage Bias on the Structure of the nsp1α of Porcine Reproductive and Respiratory Syndrome Virus
por: Ding, Yao-zhong, et al.
Publicado: (2014)

Porcine Reproductive and Respiratory Syndrome Virus nsp11 Antagonizes Type I Interferon Signaling by Targeting IRF9
por: Wang, Dang, et al.
Publicado: (2019)

Porcine Reproductive and Respiratory Syndrome Virus Antagonizes PCSK9’s Antiviral Effect via Nsp11 Endoribonuclease Activity
por: Zhang, Yujiao, et al.
Publicado: (2020)

Nuclear imprisonment of host cellular mRNA by nsp1β protein of porcine reproductive and respiratory syndrome virus
por: Han, Mingyuan, et al.
Publicado: (2017)

Porcine Reproductive and Respiratory Syndrome Virus nsp1β Stabilizes HIF-1α to Enhance Viral Replication
por: Pang, Yu, et al.
Publicado: (2022)

Effect of porcine circovirus type 2a or 2b on infection kinetics and pathogenicity of two genetically divergent strains of porcine reproductive and respiratory syndrome virus in the conventional pig model
por: Opriessnig, Tanja, et al.
Publicado: (2012)

Nonstructural proteins nsp2TF and nsp2N of porcine reproductive and respiratory syndrome virus (PRRSV) play important roles in suppressing host innate immune responses
por: Li, Y., et al.
Publicado: (2018)

Interleukin-2 enhancer binding factor 2 interacts with the nsp9 or nsp2 of porcine reproductive and respiratory syndrome virus and exerts negatively regulatory effect on the viral replication
por: Wen, Xuexia, et al.
Publicado: (2017)

Identification of two auto-cleavage products of nonstructural protein 1 (nsp1) in porcine reproductive and respiratory syndrome virus infected cells: nsp1 function as interferon antagonist
por: Chen, Z., et al.
Publicado: (2010)

Coronavirus Endoribonuclease Activity in Porcine Epidemic Diarrhea Virus Suppresses Type I and Type III Interferon Responses
por: Deng, Xufang, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ee5ealrui8d6qunu9d8j5mad22