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Endocytosis of the receptor-binding domain of SARS-CoV spike protein together with virus receptor ACE2

Cell entry of severe acute respiratory syndrome coronavirus (SARS-CoV) is mediated by the viral spike (S) protein. Amino acids 319–510 on the S protein have been mapped as the receptor-binding domain (RBD), which mediates binding to the SARS-CoV receptor angiotensin converting enzyme 2 (ACE2) on SAR...

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Detalles Bibliográficos
Autores principales: Wang, Shunxin, Guo, Feng, Liu, Kangtai, Wang, Hongliang, Rao, Shuan, Yang, Peng, Jiang, Chengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114441/
https://www.ncbi.nlm.nih.gov/pubmed/18554741
http://dx.doi.org/10.1016/j.virusres.2008.03.004