Mutation of neutralizing/antibody-dependent enhancing epitope on spike protein and 7b gene of feline infectious peritonitis virus: Influences of viral replication in monocytes/macrophages and virulence in cats

We previously prepared neutralizing monoclonal antibody (MAb)-resistant (mar) mutant viruses using a laboratory strain feline infectious peritonitis virus (FIPV) 79-1146 (Kida et al., 1999). Mar mutant viruses are mutated several amino acids of the neutralizing epitope of Spike protein, compared wit...

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Detalles Bibliográficos
Autores principales: Takano, Tomomi, Tomiyama, Yoshika, Katoh, Yasuichiroh, Nakamura, Michiyo, Satoh, Ryoichi, Hohdatsu, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114493/
https://www.ncbi.nlm.nih.gov/pubmed/21211540
http://dx.doi.org/10.1016/j.virusres.2010.12.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114493/
https://www.ncbi.nlm.nih.gov/pubmed/21211540
http://dx.doi.org/10.1016/j.virusres.2010.12.020

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