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siRNA-containing liposomes modified with polyarginine effectively silence the targeted gene

Development of RNA interference (RNAi) technology utilizing the short interfering RNA sequences (siRNA) based ‘targeted’ therapeutics has focused on creating methods for delivering siRNAs to cells and for enhancing siRNA stability in vitro and in vivo. Here, we describe a novel approach for siRNA ce...

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Detalles Bibliográficos
Autores principales: Zhang, Chunling, Tang, Ning, Liu, XingJun, Liang, Wei, Xu, Wei, Torchilin, Vladimir P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114600/
https://www.ncbi.nlm.nih.gov/pubmed/16545478
http://dx.doi.org/10.1016/j.jconrel.2006.01.022