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Empowering Retinal Gene Therapy with a Specific Promoter for Human Rod and Cone ON-Bipolar Cells

Optogenetic gene therapy holds promise to restore high-quality vision in blind patients and recently reached clinical trials. Although the ON-bipolar cells, the first retinal interneurons, make the most attractive targets for optogenetic vision restoration, they have remained inaccessible to human g...

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Detalles Bibliográficos
Autores principales: Hulliger, Elmar Carlos, Hostettler, Simon Manuel, Kleinlogel, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114634/
https://www.ncbi.nlm.nih.gov/pubmed/32258214
http://dx.doi.org/10.1016/j.omtm.2020.03.003