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PEDV nsp16 negatively regulates innate immunity to promote viral proliferation

Type-I IFNs (IFN-I) provide a key mediator of innate antiviral response during virus proliferation. Porcine epidemic diarrhea virus (PEDV), which causes diarrhea in swine of all ages, is a worldwide-distributed alphacoronavirus with economic importance. Here, we screened PEDV RNA modification enzyme...

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Detalles Bibliográficos
Autores principales: Shi, Peidian, Su, Yanxin, Li, Ruiqiao, Liang, Zhixuan, Dong, Shuren, Huang, Jinhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114654/
https://www.ncbi.nlm.nih.gov/pubmed/30849413
http://dx.doi.org/10.1016/j.virusres.2019.03.005