Macromolecular prodrugs of ribavirin: Polymer backbone defines blood safety, drug release, and efficacy of anti-inflammatory effects

Macromolecular (pro)drugs hold much promise as broad-spectrum antiviral agents as either microbicides or carriers for intracellular delivery of antiviral drugs. Intriguing opportunity exists in combining the two modes of antiviral activity in the same polymer structure such that the same polymer act...

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Detalles Bibliográficos
Autores principales: Zuwala, Kaja, Riber, Camilla F., Løvschall, Kaja Borup, Andersen, Anna H.F., Sørensen, Lise, Gajda, Paulina, Tolstrup, Martin, Zelikin, Alexander N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114659/
https://www.ncbi.nlm.nih.gov/pubmed/29432822
http://dx.doi.org/10.1016/j.jconrel.2018.02.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114659/
https://www.ncbi.nlm.nih.gov/pubmed/29432822
http://dx.doi.org/10.1016/j.jconrel.2018.02.012

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