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A novel population of memory‐activated natural killer cells associated with low parasitaemia in Plasmodium falciparum‐exposed sickle‐cell trait children

OBJECTIVES: The sickle‐cell trait phenotype is associated with protection from malaria. Multiple molecular mechanisms have been proposed to explain this protection, but the role of the host immune system has been poorly investigated. We hypothesised that cellular immunity to malaria may develop diff...

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Detalles Bibliográficos
Autores principales: Loiseau, Claire, Doumbo, Ogobara K, Traore, Boubacar, Brady, Jamie L, Proietti, Carla, de Sousa, Karina P, Crompton, Peter D, Doolan, Denise L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114700/
https://www.ncbi.nlm.nih.gov/pubmed/32257211
http://dx.doi.org/10.1002/cti2.1125