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Synthesis and Biological Activities of Some New Benzotriazinone Derivatives Based on Molecular Docking; Promising HepG2 Liver Carcinoma Inhibitors

[Image: see text] In one-pot strategy, diazotization of methyl anthranilate 5 followed by addition of amino acid ester hydrochloride, we have prepared methyl-2-(4-oxobenzotriazin-3(4H)-yl)alkanoates 6a–c. Starting with hydrazides 7a,b, N-alkyl-2-(4-oxobenzotriazin-3(4H)-yl)alkanamides 9–10(a–h) and...

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Detalles Bibliográficos
Autores principales: El Rayes, Samir M., Ali, Ibrahim A. I., Fathalla, Walid, Mahmoud, Mostafa A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114758/
https://www.ncbi.nlm.nih.gov/pubmed/32258913
http://dx.doi.org/10.1021/acsomega.0c00116