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Lamina-associated domains: peripheral matters and internal affairs

At the nuclear periphery, associations of chromatin with the nuclear lamina through lamina-associated domains (LADs) aid functional organization of the genome. We review the organization of LADs and provide evidence of LAD heterogeneity from cell ensemble and single-cell data. LADs are typically rep...

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Detalles Bibliográficos
Autores principales: Briand, Nolwenn, Collas, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114793/
https://www.ncbi.nlm.nih.gov/pubmed/32241294
http://dx.doi.org/10.1186/s13059-020-02003-5