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Lamina-associated domains: peripheral matters and internal affairs
At the nuclear periphery, associations of chromatin with the nuclear lamina through lamina-associated domains (LADs) aid functional organization of the genome. We review the organization of LADs and provide evidence of LAD heterogeneity from cell ensemble and single-cell data. LADs are typically rep...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114793/ https://www.ncbi.nlm.nih.gov/pubmed/32241294 http://dx.doi.org/10.1186/s13059-020-02003-5 |