Cargando…

MiR-30a and miR-379 modulate retinoic acid pathway by targeting DNA methyltransferase 3B in oral cancer

BACKGROUND: Epigenetic silencing of retinoic acid (RA) signaling-related genes have been linked with the pathogenesis and clinical outcome in oral squamous cell carcinoma (OSCC) carcinogenesis. However, the precise mechanisms underlying the abnormal silencing of RA signaling-related genes in OSCC ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Shiah, Shine-Gwo, Hsiao, Jenn-Ren, Chang, Hsiao-Ju, Hsu, Yuan-Ming, Wu, Guan-Hsun, Peng, Hsuan-Yu, Chou, Sung-Tau, Kuo, Ching-Chuan, Chang, Jang-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114797/
https://www.ncbi.nlm.nih.gov/pubmed/32238162
http://dx.doi.org/10.1186/s12929-020-00644-z