Metabolic regulation of calcium pumps in pancreatic cancer: role of phosphofructokinase-fructose-bisphosphatase-3 (PFKFB3)

BACKGROUND: High glycolytic rate is a hallmark of cancer (Warburg effect). Glycolytic ATP is required for fuelling plasma membrane calcium ATPases (PMCAs), responsible for extrusion of cytosolic calcium, in pancreatic ductal adenocarcinoma (PDAC). Phosphofructokinase-fructose-bisphosphatase-3 (PFKFB...

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Detalles Bibliográficos
Autores principales: Richardson, D. A., Sritangos, P., James, A. D., Sultan, A., Bruce, J. I. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114799/
https://www.ncbi.nlm.nih.gov/pubmed/32266066
http://dx.doi.org/10.1186/s40170-020-0210-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114799/
https://www.ncbi.nlm.nih.gov/pubmed/32266066
http://dx.doi.org/10.1186/s40170-020-0210-2

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