The SARS coronavirus spike glycoprotein is selectively recognized by lung surfactant protein D and activates macrophages

The severe acute respiratory syndrome coronavirus (SARS-CoV) infects host cells with its surface glycosylated spike-protein (S-protein). Here we expressed the SARS-CoV S-protein to investigate its interactions with innate immune mechanisms in the lung. The purified S-protein was detected as a 210 kD...

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Detalles Bibliográficos
Autores principales: Leth-Larsen, Rikke, Zhong, Fei, Chow, Vincent T.K., Holmskov, Uffe, Lu, Jinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier GmbH. 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114820/
https://www.ncbi.nlm.nih.gov/pubmed/17412287
http://dx.doi.org/10.1016/j.imbio.2006.12.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114820/
https://www.ncbi.nlm.nih.gov/pubmed/17412287
http://dx.doi.org/10.1016/j.imbio.2006.12.001

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