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The SARS coronavirus spike glycoprotein is selectively recognized by lung surfactant protein D and activates macrophages
The severe acute respiratory syndrome coronavirus (SARS-CoV) infects host cells with its surface glycosylated spike-protein (S-protein). Here we expressed the SARS-CoV S-protein to investigate its interactions with innate immune mechanisms in the lung. The purified S-protein was detected as a 210 kD...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier GmbH.
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114820/ https://www.ncbi.nlm.nih.gov/pubmed/17412287 http://dx.doi.org/10.1016/j.imbio.2006.12.001 |