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Enhanced Production of Herpes Simplex Virus 1 Amplicon Vectors by Gene Modification and Optimization of Packaging Cell Growth Medium

Herpes simplex virus 1 (HSV-1)-derived amplicon vectors are unique in their ability to accommodate large DNA molecules allowing whole genomic loci to be included with all of their regulatory elements. Additional advantages of these amplicons include their minimal toxicity and ability to persist as e...

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Detalles Bibliográficos
Autores principales: Fernández-Frías, Iván, Pérez-Luz, Sara, Díaz-Nido, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114837/
https://www.ncbi.nlm.nih.gov/pubmed/32258212
http://dx.doi.org/10.1016/j.omtm.2020.03.005