AAV6 Vexosomes Mediate Robust Suicide Gene Delivery in a Murine Model of Hepatocellular Carcinoma

During recombinant Adeno-associated virus (AAV) production, a proportionately large amount of vectors is released in the culture supernatant, which is often discarded. It has been shown that these vectors often associate with vesiculated structures, such as exosomes. Exosome-associated AAV (vexosome...

Descripción completa

Detalles Bibliográficos
Autores principales: Khan, Nusrat, Maurya, Shubham, Bammidi, Sridhar, Jayandharan, Giridhara R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114838/
https://www.ncbi.nlm.nih.gov/pubmed/32258213
http://dx.doi.org/10.1016/j.omtm.2020.03.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114838/
https://www.ncbi.nlm.nih.gov/pubmed/32258213
http://dx.doi.org/10.1016/j.omtm.2020.03.006

Ejemplares similares