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Atractylenolide I Induces Apoptosis and Suppresses Glycolysis by Blocking the JAK2/STAT3 Signaling Pathway in Colorectal Cancer Cells

Colorectal cancer (CRC) is the third most common cancer worldwide and is associated with a poor clinical outcome and survival. Therefore, the development of novel therapeutic agents for CRC is imperative. Atractylenolide I (AT-I) is a sesquiterpenoid lactone derivative of Rhizoma Atractylodis macroc...

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Detalles Bibliográficos
Autores principales: Li, Yanxi, Wang, Yongpeng, Liu, Zhexian, Guo, Xingqi, Miao, Ziwei, Ma, Siping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114890/
https://www.ncbi.nlm.nih.gov/pubmed/32273843
http://dx.doi.org/10.3389/fphar.2020.00273