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Transcriptomic Analysis of Glioma Based on IDH Status Identifies ACAA2 as a Prognostic Factor in Lower Grade Glioma

BACKGROUND: Glioma is the most common and lethal tumor in the central nervous system (CNS). More than 70% of WHO grade II/III gliomas were found to harbor isocitrate dehydrogenase (IDH) mutations which generated targetable metabolic vulnerabilities. Focusing on the metabolic vulnerabilities, some ta...

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Detalles Bibliográficos
Autores principales: Wu, Chenxing, Song, Hongwang, Fu, Xiaojun, Li, Shouwei, Jiang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115055/
https://www.ncbi.nlm.nih.gov/pubmed/32280672
http://dx.doi.org/10.1155/2020/1086792