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Development of high-growth influenza H7N9 prepandemic candidate vaccine viruses in suspension MDCK cells
BACKGROUND: Influenza vaccine manufacturers traditionally use egg-derived candidate vaccine viruses (CVVs) to produce high-yield influenza viruses for seasonal or pandemic vaccines; however, these egg-derived CVVs need an adaptation process for the virus to grow in mammalian cells. The low yields of...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115086/ https://www.ncbi.nlm.nih.gov/pubmed/32241276 http://dx.doi.org/10.1186/s12929-020-00645-y |