A Strategic Target Rescues Trimethoprim Sensitivity in Escherichia coli

Trimethoprim, a preferred treatment for urinary tract infections, is becoming obsolete owing to the rapid dissemination of resistant E. coli. Although direct resistance mechanisms such as overexpression of a mutant FolA and dfr enzymes are well characterized, associated alterations that drive or sus...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhosle, Amrisha, Datey, Akshay, Chandrasekharan, Giridhar, Singh, Deepshikha, Chakravortty, Dipshikha, Chandra, Nagasuma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115098/
https://www.ncbi.nlm.nih.gov/pubmed/32240953
http://dx.doi.org/10.1016/j.isci.2020.100986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115098/
https://www.ncbi.nlm.nih.gov/pubmed/32240953
http://dx.doi.org/10.1016/j.isci.2020.100986

Ejemplares similares