Homeostatic Cytokines Drive Epigenetic Reprogramming of Activated T Cells into a “Naive-Memory” Phenotype

Primary stimulation of T cells is believed to trigger unidirectional differentiation from naive to effector and memory subsets. Here we demonstrate that IL-7 can drive the phenotypic reversion of recently differentiated human central and effector memory CD8(+) T cells into a naive-like phenotype. Th...

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Detalles Bibliográficos
Autores principales: Frumento, Guido, Verma, Kriti, Croft, Wayne, White, Andrea, Zuo, Jianmin, Nagy, Zsuzsanna, Kissane, Stephen, Anderson, Graham, Moss, Paul, Chen, Frederick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115140/
https://www.ncbi.nlm.nih.gov/pubmed/32240954
http://dx.doi.org/10.1016/j.isci.2020.100989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115140/
https://www.ncbi.nlm.nih.gov/pubmed/32240954
http://dx.doi.org/10.1016/j.isci.2020.100989

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