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Succinate Dehydrogenase-Regulated Phosphoenolpyruvate Carboxykinase Sustains Copulation Fitness in Aging C. elegans Males

Dysregulated metabolism accelerates reduced decision-making and locomotor ability during aging. To identify mechanisms for delaying behavioral decline, we investigated how C. elegans males sustain their copulatory behavior during early to mid-adulthood. We found that in mid-aged males, gluco-/glycer...

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Detalles Bibliográficos
Autores principales: Goncalves, Jimmy, Wan, Yufeng, Guo, Xiaoyan, Rha, Kyoungsun, LeBoeuf, Brigitte, Zhang, Liusuo, Estler, Kerolayne, Garcia, L. René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115159/
https://www.ncbi.nlm.nih.gov/pubmed/32240955
http://dx.doi.org/10.1016/j.isci.2020.100990