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Mechanisms of impaired pancreatic β-cell function in high-fat diet-induced obese mice: The role of endoplasmic reticulum stress
The aim of the study was to examine whether there was excessive endoplasmic reticulum stress (ERs) in the islets of high-fat diet (HFD)-induced obese mice, as well as the effects of ERs on β-cell function. Male C57BL/6J mice were fed a HFD for 16 weeks. Pancreatic β-cell function was evaluated using...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115219/ https://www.ncbi.nlm.nih.gov/pubmed/32323766 http://dx.doi.org/10.3892/mmr.2020.11013 |