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Mechanisms of impaired pancreatic β-cell function in high-fat diet-induced obese mice: The role of endoplasmic reticulum stress

The aim of the study was to examine whether there was excessive endoplasmic reticulum stress (ERs) in the islets of high-fat diet (HFD)-induced obese mice, as well as the effects of ERs on β-cell function. Male C57BL/6J mice were fed a HFD for 16 weeks. Pancreatic β-cell function was evaluated using...

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Detalles Bibliográficos
Autores principales: Yi, Xiaoqing, Cai, Xuan, Wang, Sisi, Xiao, Yanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115219/
https://www.ncbi.nlm.nih.gov/pubmed/32323766
http://dx.doi.org/10.3892/mmr.2020.11013