Identification and characterization of novel neutralizing epitopes in the receptor-binding domain of SARS-CoV spike protein: Revealing the critical antigenic determinants in inactivated SARS-CoV vaccine

The spike (S) protein of severe acute respiratory syndrome coronavirus (SARS-CoV) is considered as a major antigen for vaccine design. We previously demonstrated that the receptor-binding domain (RBD: residues 318–510) of S protein contains multiple conformation-dependent neutralizing epitopes (Conf...

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Detalles Bibliográficos
Autores principales: He, Yuxian, Li, Jingjing, Du, Lanying, Yan, Xuxia, Hu, Guangan, Zhou, Yusen, Jiang, Shibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115380/
https://www.ncbi.nlm.nih.gov/pubmed/16725238
http://dx.doi.org/10.1016/j.vaccine.2006.04.054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115380/
https://www.ncbi.nlm.nih.gov/pubmed/16725238
http://dx.doi.org/10.1016/j.vaccine.2006.04.054

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