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A risk-assessment model to rate the occurrence and relevance of adventitious agents in the production of influenza vaccines

Influenza vaccine production has traditionally relied on the use of embryonated chicken eggs for virus isolation and propagation, but recently, cell-culture-derived manufacturing methods have been introduced. During influenza vaccine production, by either conventional or cell culture methods, there...

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Detalles Bibliográficos
Autor principal: Gregersen, Jens-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115387/
https://www.ncbi.nlm.nih.gov/pubmed/18468737
http://dx.doi.org/10.1016/j.vaccine.2008.03.076